FASL anticorps

N° du produit ABIN636623

L’anticorps anti-FASL Polyclonal Chèvre est utilisé pour la détection de FASL dans des échantillons de Humain. Il a été validé pour WB, ELISA et Inhibition.

Aperçu rapide pour FASL anticorps (ABIN636623)

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FASL est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Détail du produit anti-FASL anticorps

Purification: Purified

Immunogène: FasL antibody was raised in goat using highly pure recombinant human FasL/Apo1 L as the immunogen.

Information d'application

Indications d'application: ELISA: 0.5-2 µg/mL, Inhibition: 0.08-0.1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur FASL

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Autre désignation: FasL

Sujet: Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.

Poids moléculaire: 17.6 kDa (predicted detection band MW)

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity