IGFBP5 anticorps
Aperçu rapide pour IGFBP5 anticorps (ABIN636652)
Antigène
Voir toutes IGFBP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified
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Immunogène
- IGF BP5 antibody was raised in rabbit using highly pure recombinant human IGF-BP5 as the immunogen.
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Indications d'application
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- IGFBP5 (Insulin-Like Growth Factor Binding Protein 5 (IGFBP5))
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Autre désignation
- IGF BP5
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Sujet
- IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells.
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Poids moléculaire
- 28.6 kDa (predicted detection band MW)
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Pathways
- Signalisation WNT, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
Antigène
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