IFNA anticorps
Aperçu rapide pour IFNA anticorps (ABIN639854)
Antigène
Voir toutes IFNA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse Anti-Chicken IFN-alpha
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Specificité
- DS-MB-01578 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFN I) or Type II Interferon (IFN II). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. DS-MB-01578 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
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Attributs du produit
- Cytokines/Chemokines/Growth Factors/Receptors
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Purification
- Purified
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Immunogène
- Recombinant chicken Interferon alpha
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Isotype
- IgG1
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Indications d'application
- ELISA, Western Blotting
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 0.5 mg/ml
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Buffer
- Phosphate buffered saline
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- IFNA (Interferon alpha (IFNA))
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Autre désignation
- Interferon-alpha (IFNa)
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Pathways
- Signalistation JAK/STAT, Signalisation TLR, Hepatitis C, Inflammasome
Antigène
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