UHRF1 anticorps (AA 229-257)

N° du produit ABIN652792

Détail du produit anti-UHRF1 anticorps

Antigène: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Épitope: AA 229-257

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UHRF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UHRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human UHRF1.

Clone: RB21516

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur UHRF1

Antigène: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Autre désignation: UHRF1 (UHRF1 Produits)

Synonymes: anticorps ICBP90, anticorps Np95, anticorps RNF106, anticorps hNP95, anticorps hUHRF1, anticorps AL022808, anticorps NP95, anticorps fb97f09, anticorps wu:fb97f09, anticorps zgc:63539, anticorps UHRF1, anticorps ubiquitin like with PHD and ring finger domains 1, anticorps ubiquitin-like, containing PHD and RING finger domains, 1, anticorps ubiquitin-like with PHD and ring finger domains 1, anticorps UHRF1, anticorps Uhrf1, anticorps uhrf1

Sujet: UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone acetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.

Poids moléculaire: 89814

ID gène: 29128

NCBI Accession: NP_001041666, NP_037414

UniProt: Q96T88