LFNG anticorps (AA 86-114)

N° du produit ABIN653477

Détail du produit anti-LFNG anticorps

Antigène: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Épitope: AA 86-114

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LFNG est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LFNG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human LFNG.

Clone: RB24078

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur LFNG

Antigène: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Autre désignation: LFNG (LFNG Produits)

Synonymes: anticorps SCDO3, anticorps AW061165, anticorps id:ibd2614, anticorps id:ibd5029, anticorps id:ibd5138, anticorps l-fng, anticorps wu:fc69h02, anticorps wu:fi34c01, anticorps LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, anticorps LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog, anticorps LFNG, anticorps Lfng, anticorps lfng.S, anticorps lfng

Sujet: LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).

Poids moléculaire: 41773

ID gène: 3955

NCBI Accession: NP_001035257, NP_001035258, NP_001159827, NP_002295

UniProt: Q8NES3

Pathways: Signalisation Notch