HFE2 anticorps (C-Term)
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- Antigène Voir toutes HFE2 Anticorps
- HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
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Épitope
- AA 308-338, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HFE2 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Homologie
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This HFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-338 amino acids from the C-terminal region of human HFE2.
- Clone
- RB22186
- Isotype
- Ig Fraction
- Top Product
- Discover our top product HFE2 Anticorps primaire
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- Indications d'application
- WB: 1:1000. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
- Autre désignation
- HFE2 (HFE2 Produits)
- Synonymes
- anticorps HFE2A, anticorps HJV, anticorps JH, anticorps RGMC, anticorps HFE2, anticorps DKFZp468F2322, anticorps 2310035L15Rik, anticorps 5230400G09Rik, anticorps AI414844, anticorps AI789733, anticorps DL-M, anticorps Rgmc, anticorps hemojuvelin, anticorps RGMr, anticorps hjv, anticorps id:ibd3464, anticorps wu:fb38f10, anticorps zgc:136698, anticorps hemochromatosis type 2 (juvenile), anticorps hemochromatosis type 2, anticorps HFE2, anticorps Hfe2, anticorps hfe2
- Sujet
- HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.
- Poids moléculaire
- 45080
- ID gène
- 148738
- NCBI Accession
- NP_660320, NP_973733, NP_998817, NP_998818
- UniProt
- Q6ZVN8
- Pathways
- Transition Metal Ion Homeostasis
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