HDAC2 anticorps (AA 410-439)

N° du produit ABIN653718

Cet anticorps anti-HDAC2 est un anticorps Lapin Polyclonal détectant HDAC2 dans WB, IF, IHC (p) et FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour HDAC2 anticorps (AA 410-439) (ABIN653718)

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB24526

Détail du produit anti-HDAC2 anticorps

Épitope: AA 410-439

Homologie: C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the Central region of human HDAC2.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HDAC2 (ABIN653718)

Leucker, Nomura, Kim, Bhatta, Wang, Wecker, Jandu, Santhanam, Berkowitz, Romer, Pandey: "Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6." dans: American journal of physiology. Heart and circulatory physiology, Vol. 312, Issue 4, pp. H711-H720, (2017) (PubMed).

Détails sur HDAC2

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Autre désignation: HDAC2

Sujet: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Poids moléculaire: 55364

ID gène: 3066

NCBI Accession: NP_001518

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2