Neuroserpin anticorps (N-Term)

N° du produit ABIN654346

Détail du produit anti-Neuroserpin anticorps

Antigène: Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))

Épitope: AA 19-45, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuroserpin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SERPINI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human SERPINI1.

Clone: RB28079

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Neuroserpin

Antigène: Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))

Autre désignation: SERPINI1 (SERPINI1 Produits)

Synonymes: anticorps PI12, anticorps neuroserpin, anticorps AI837402, anticorps Ns, anticorps PI-12, anticorps Spi17, anticorps CG9453, anticorps Dmel\\CG9453, anticorps Serp2, anticorps Sp4, anticorps Spn4, anticorps Spn4A, anticorps dSerp2, anticorps sp4, anticorps spn4, anticorps raPIT5a, anticorps SERPINI1, anticorps pi12, anticorps serpini1l, anticorps si:ch211-167c22.4, anticorps serpin family I member 1, anticorps serine (or cysteine) peptidase inhibitor, clade I, member 1, anticorps Serpin 42Da, anticorps serpin peptidase inhibitor, clade I (neuroserpin), member 1, anticorps serpin family I member 1 L homeolog, anticorps SERPINI1, anticorps Serpini1, anticorps Spn42Da, anticorps serpini1, anticorps serpini1.L

Sujet: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 46427

ID gène: 5274

NCBI Accession: NP_001116224, NP_005016

UniProt: Q99574

Pathways: Regulation of Hormone Metabolic Process