PSMB11 anticorps (C-Term)

N° du produit ABIN655286

Détail du produit anti-PSMB11 anticorps

Antigène: PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

Épitope: AA 250-278, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PSMB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the C-terminal region of human PSMB11.

Clone: RB28790

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PSMB11

Antigène: PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

Autre désignation: PSMB11 (PSMB11 Produits)

Synonymes: anticorps BETA5T, anticorps 5830406J20Rik, anticorps beta5t, anticorps proteasome subunit beta 11, anticorps proteasome (prosome, macropain) subunit, beta type, 11, anticorps PSMB11, anticorps Psmb11

Sujet: Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6, MIM 600307), beta-2 (PSMB7, MIM 604030), and beta-5 (PSMB5, MIM 600306). Three additional subunits, beta-1i (PSMB9, MIM 177045), beta-2i (PSMB10, MIM 176847), and beta-5i (PSMB8, MIM 177046), are induced by gamma-interferon (IFNG, MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 [PubMed 17540904]).

Poids moléculaire: 32530

ID gène: 122706

NCBI Accession: NP_001093250

UniProt: A5LHX3