CD8B anticorps (C-Term)

N° du produit ABIN655897

Cet anticorps Lapin Polyclonal détecte spécifiquement CD8B dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CD8B anticorps (C-Term) (ABIN655897)

Antigène: CD8B (CD8b Molecule (CD8B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD8B est non-conjugé

Application: Western Blotting (WB)

Clone: RB14077

Détail du produit anti-CD8B anticorps

Épitope: AA 141-167, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CD8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-167 amino acids from the C-terminal region of human CD8B1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CD8B

Antigène: CD8B (CD8b Molecule (CD8B))

Autre désignation: CD8B1

Sujet: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Poids moléculaire: 23722

ID gène: 926

NCBI Accession: NP_001171571, NP_004922, NP_742099, NP_742100, NP_757362

UniProt: P10966

Pathways: TCR Signaling