FASL anticorps

N° du produit ABIN6566520

Cet anticorps anti-FASL Polyclonal Lapin (ABIN6566520) détecte spécifiquement FASL dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FASL anticorps (ABIN6566520)

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FASL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FASL anticorps

Purification: Affinity purification

Immunogène: A synthetic peptide of human FASLG

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FASL

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Autre désignation: FASLG

Sujet:

Synonyms: ALPS1B,Apoptosis (APO 1) antigen ligand 1,Apoptosis antigen ligand 1,Apoptosis antigen ligand,APT1LG1,APTL,CD178,CD178 antigen,CD95 ligand,CD95-L,CD95L,CD95L protein,Fas antigen ligand,Fas L,Fas ligand (TNF superfamily member 6),Fas ligand,FASL,Fasl Fas ligand (TNF superfamily member 6),FASLG,Generalized lymphoproliferative disease,Gld,soluble form,TNFL6,TNFSF6,Tumor necrosis factor (ligand) superfamily member 6,Tumor necrosis factor ligand superfamily member 6

Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Poids moléculaire:

Observed_MW: 45kDa

Calculated_MW: 14kDa/31kDa

ID gène: 356

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity