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GCK anticorps

GCK Reactivité: Humain, Souris, Rat IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6566589
  • Antigène Voir toutes GCK Anticorps
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Reactivité
    • 69
    • 30
    • 20
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 65
    • 8
    Lapin
    Clonalité
    • 68
    • 5
    Polyclonal
    Conjugué
    • 39
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp GCK est non-conjugé
    Application
    • 58
    • 36
    • 34
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human GCK
    Isotype
    IgG
    Top Product
    Discover our top product GCK Anticorps primaire
  • Indications d'application
    IF 1:20 - 1:100
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Autre désignation
    GCK (GCK Produits)
    Synonymes
    anticorps FGQTL3, anticorps GK, anticorps GLK, anticorps HHF3, anticorps HK4, anticorps HKIV, anticorps HXKP, anticorps LGLK, anticorps MODY2, anticorps Gk, anticorps Gls006, anticorps GCK, anticorps BA4487, anticorps glk, anticorps hk4, anticorps hhf3, anticorps hkiv, anticorps hxkp, anticorps gck-A, anticorps mody2, anticorps glucokinase, anticorps GLUKA, anticorps RNGK2, anticorps glucokinase, anticorps glucokinase (hexokinase 4) L homeolog, anticorps glucokinase (hexokinase 4), anticorps GCK, anticorps Gck, anticorps glcK, anticorps Bphyt_1025, anticorps Halhy_6548, anticorps gk, anticorps gck.L, anticorps gck
    Sujet

    Synonyms: ATP:D-hexose 6-phosphotransferase,FGQTL3,GCK,GK,GLK,Glucokinase,Hexokinase D pancreatic isozyme,Hexokinase type IV,Hexokinase-4,Hexokinase-D,HHF3,HK IV,HK4,HKIV,HXK4,HXKP,LGLK,MODY2

    Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

    Poids moléculaire

    Calculated_MW: 52kDa

    ID gène
    2645
    UniProt
    P35557
    Pathways
    Signalisation MAPK, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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