PPARA anticorps (AA 153-181)

N° du produit ABIN656834

L’anticorps Lapin Polyclonal anti-PPARA a été validé pour WB et FACS. Il convient pour détecter PPARA dans des échantillons de Souris. Il y a 1 publication disponible.

Aperçu rapide pour PPARA anticorps (AA 153-181) (ABIN656834)

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARA est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB21340

Détail du produit anti-PPARA anticorps

Épitope: AA 153-181

Homologie: Rat, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PPARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human PPARA.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PPARA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-PPARA (ABIN656834)

Spruiell, Richardson, Cullen, Awumey, Gonzalez, Gyamfi: "Role of pregnane X receptor in obesity and glucose homeostasis in male mice." dans: The Journal of biological chemistry, Vol. 289, Issue 6, pp. 3244-61, (2014) (PubMed).

Détails sur PPARA

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Autre désignation: PPARA

Sujet: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Poids moléculaire: 52225

ID gène: 5465

NCBI Accession: NP_001001928, NP_005027

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C