CDC45 anticorps
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- Antigène Voir toutes CDC45 Anticorps
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDC45 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human CDC45 (NP_003495.1).
- Isotype
- IgG
- Top Product
- Discover our top product CDC45 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
- Autre désignation
- CDC45 (CDC45 Produits)
- Synonymes
- anticorps cdc45l, anticorps cdc45l2, anticorps porc-pi-1, anticorps CDC45L, anticorps CDC45L2, anticorps PORC-PI-1, anticorps Cdc45l, anticorps cell division cycle 45, anticorps cell division cycle 45 S homeolog, anticorps cell division cycle 45 L homeolog, anticorps cdc45, anticorps CDC45, anticorps cdc45.S, anticorps Cdc45, anticorps cdc45.L
- Sujet
- The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
- Poids moléculaire
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Observed_MW: 60kDa
Calculated_MW: 60kDa/65kDa/68kDa
- ID gène
- 8318
- UniProt
- O75419
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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