IRAK4 anticorps

N° du produit ABIN6570285

L’anticorps Lapin Polyclonal anti-IRAK4 a été validé pour WB et IHC. Il convient pour détecter IRAK4 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IRAK4 anticorps (ABIN6570285)

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IRAK4 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human IRAK4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IRAK4

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Autre désignation: IRAK4

Sujet:

Synonyms: IL-1 receptor-associated kinase 4,Interleukin 1 receptor associated kinase 4 mutant form 1,Interleukin-1 receptor-associated kinase 4,Interleukin1 receptor associated kinase 4,IPD1,IRAK 4,IRAK-4,IRAK4,IRAK4 mutated form 1,IRAK4,LOC 51135,NY REN 64,NY REN 64 antigen,NY-REN-64,REN64,Renal carcinoma antigen NY-REN-64

Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 55kDa

Calculated_MW: 37kDa/51kDa

ID gène: 51135

UniProt: Q9NWZ3

Pathways: Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades