SKAP2 anticorps

N° du produit ABIN6570442

Détail du produit anti-SKAP2 anticorps

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKAP2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SKAP2 (NP_003921.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SKAP2

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Autre désignation: SKAP2 (SKAP2 Produits)

Synonymes: anticorps scap2, anticorps 2610021A10Rik, anticorps AA960083, anticorps BB137539, anticorps RA70, anticorps SKAP-HOM, anticorps Saps, anticorps Scap2, anticorps mSKAP55R, anticorps PRAP, anticorps SAPS, anticorps SCAP2, anticorps SKAP55R, anticorps Scap55r, anticorps SKAP55, anticorps si:dz227h09.6, anticorps si:dz31b14.4, anticorps zgc:158223, anticorps zgc:65975, anticorps src kinase associated phosphoprotein 2 L homeolog, anticorps SRC kinase associated phosphoprotein 2, anticorps src family associated phosphoprotein 2, anticorps src kinase associated phosphoprotein 2, anticorps skap2.L, anticorps CCC13826_0176, anticorps Skap2, anticorps SKAP2, anticorps skap2

Sujet: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 50kDa

Calculated_MW: 41kDa

ID gène: 8935

UniProt: O75563