XPC anticorps

N° du produit ABIN5964337

Cet anticorps anti-XPC Polyclonal Lapin (ABIN5964337) détecte spécifiquement XPC dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour XPC anticorps (ABIN5964337)

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPC est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-XPC anticorps

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human XPC (NP_004619.3).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur XPC

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Autre désignation: XPC

Sujet: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 130kDa

Calculated_MW: 15kDa/101kDa/105kDa

ID gène: 7508

UniProt: Q01831

Pathways: Signalisation p53, Réparation de l'ADN