RNF34 anticorps

N° du produit ABIN6571814

Détail du produit anti-RNF34 anticorps

Antigène: RNF34 (Ring Finger Protein 34 (RNF34))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF34 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human RNF34

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNF34

Antigène: RNF34 (Ring Finger Protein 34 (RNF34))

Autre désignation: RNF34 (RNF34 Produits)

Synonymes: anticorps CARP-1, anticorps CARP1, anticorps RFI, anticorps RIF, anticorps RIFF, anticorps hRFI, anticorps rnf34, anticorps AW061037, anticorps AW536122, anticorps BC004042, anticorps C88279, anticorps Momo, anticorps fi35g06, anticorps wu:fi35g06, anticorps zgc:114043, anticorps zgc:171755, anticorps ring finger protein 34, anticorps E3 ubiquitin-protein ligase RNF34, anticorps ring finger protein 34a, anticorps ring finger protein 34b, anticorps Residual feed intake, anticorps RNF34, anticorps rnf34, anticorps Rnf34, anticorps rnf34a, anticorps rnf34b, anticorps RFI

Sujet:

Synonyms: CARP 1,CARP-1,CARP1,Caspase regulator CARP1,Caspases-8 and -10-associated RING finger protein 1,E3 ubiquitin-protein ligase RNF34,FYVE-RING finger protein Momo,hRFI,Human RING finger homologous to inhibitor of apoptosis protein,RFI,RIF,RIFF,RING finger protein 34,RING finger protein RIFF,RNF34,RNF34

Background: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 42kDa

Calculated_MW: 41kDa

ID gène: 80196

UniProt: Q969K3