CAPN10 anticorps

N° du produit ABIN6572052

Détail du produit anti-CAPN10 anticorps

Antigène: CAPN10 (Calpain 10 (CAPN10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAPN10 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human CAPN10

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CAPN10

Antigène: CAPN10 (Calpain 10 (CAPN10))

Autre désignation: CAPN10 (CAPN10 Produits)

Synonymes: anticorps CAPN10, anticorps CANP10, anticorps NIDDM1, anticorps AW049679, anticorps Capn8, anticorps mKIAA1845, anticorps calpain 10, anticorps calpain 10 L homeolog, anticorps CAPN10, anticorps capn10.L, anticorps capn10, anticorps Capn10

Sujet:

Synonyms: Calcium activated neutral protease,Calcium activated neutral proteinase 10,Calcium-activated neutral proteinase 10,calpain like protease CAPN10,Calpain-10,Calpain10,CAN10,CANP 10,CANP10,CAPN 10,CAPN10,EC 3.4.22.,KIAA1845,NIDDM1

Background: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

Poids moléculaire:

Observed_MW: 75kDa

Calculated_MW: 15kDa/29kDa/49kDa/57kDa/60kDa/74kDa

ID gène: 11132

UniProt: Q9HC96

Pathways: Positive Regulation of Peptide Hormone Secretion