SOCS6 anticorps

N° du produit ABIN6572094

Cet anticorps Lapin Polyclonal détecte spécifiquement SOCS6 dans IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SOCS6 anticorps (ABIN6572094)

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS6 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-SOCS6 anticorps

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SOCS6 (NP_004223.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SOCS6

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Autre désignation: SOCS6

Sujet: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Poids moléculaire:

Observed_MW: 70kDa

Calculated_MW: 59kDa

ID gène: 9306

UniProt: O14544

Pathways: Signalistation JAK/STAT, Carbohydrate Homeostasis