WIPI2 anticorps (N-Term)

N° du produit ABIN657237

Détail du produit anti-WIPI2 anticorps

Antigène: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Épitope: AA 4-32, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WIPI2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This WIPI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human WIPI2.

Clone: RB33312

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-WIPI2 (ABIN657237)

Burbulla, Fitzgerald, Stegen, Westermeier, Thost, Kato, Mokranjac, Sauerwald, Martins, Woitalla, Rapaport, Riess, Proikas-Cezanne, Rasse, Krüger: "Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1." dans: Cell death & disease, Vol. 5, pp. e1180, (2014) (PubMed).

Nemazanyy, Blaauw, Paolini, Caillaud, Protasi, Mueller, Proikas-Cezanne, Russell, Guan, Nishino, Sandri, Pende, Panasyuk: "Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease." dans: EMBO molecular medicine, Vol. 5, Issue 6, pp. 870-90, (2013) (PubMed).

Détails sur WIPI2

Antigène: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Autre désignation: WIPI2 (WIPI2 Produits)

Synonymes: anticorps ATG18B, anticorps Atg21, anticorps WIPI-2, anticorps 1110018O08Rik, anticorps 2510001I10Rik, anticorps WD repeat domain, phosphoinositide interacting 2 L homeolog, anticorps WD repeat domain, phosphoinositide interacting 2, anticorps wipi2.L, anticorps WIPI2, anticorps Wipi2

Sujet: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).

Poids moléculaire: 49408

NCBI Accession: NP_001028690, NP_001028691, NP_001028692, NP_001265228, NP_056425, NP_057087

UniProt: Q9Y4P8