BTK anticorps (N-Term)

N° du produit ABIN657469

Cet anticorps Lapin Polyclonal détecte spécifiquement BTK dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour BTK anticorps (N-Term) (ABIN657469)

Antigène: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33691

Détail du produit anti-BTK anticorps

Épitope: AA 27-55, N-Term

Homologie: C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human BTK.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: BTK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur BTK

Antigène: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Autre désignation: BTK

Sujet: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Poids moléculaire: 76281

ID gène: 695

NCBI Accession: NP_000052

UniProt: Q06187

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling