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MMP2 anticorps (AA 303-331)

MMP2 Reactivité: Humain WB Hôte: Lapin Polyclonal RB33605 unconjugated
N° du produit ABIN657616
  • Antigène Voir toutes MMP2 Anticorps
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Épitope
    • 16
    • 16
    • 16
    • 11
    • 10
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 303-331
    Reactivité
    • 151
    • 80
    • 65
    • 49
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 124
    • 42
    • 1
    Lapin
    Clonalité
    • 121
    • 46
    Polyclonal
    Conjugué
    • 80
    • 14
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MMP2 est non-conjugé
    Application
    • 135
    • 59
    • 52
    • 39
    • 39
    • 37
    • 31
    • 29
    • 18
    • 15
    • 14
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    C, M, Rb, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-331 amino acids from the Central region of human MMP2.
    Clone
    RB33605
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MMP2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    MMP2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Date de péremption
    6 months
  • Chen, Liu, Gao, Hui, Yang, Zhang, Xu, Tian, Fan: "Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus." dans: Tumour biology, Vol. 39, Issue 5, pp. 1010428317708270, (2017) (PubMed).

    Dai, Duan, Duan, Zhou, He, Tu, Shen: "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer." dans: Biochemical and biophysical research communications, (2015) (PubMed).

    Shi, Shang, Pan, Wang, Jiang, Hao, Zhang, Cai, Xu, Zhan, Wang: "Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 23, pp. 6153-62, (2014) (PubMed).

  • Antigène
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Autre désignation
    MMP2 (MMP2 Produits)
    Synonymes
    anticorps 2-MMP, anticorps CG1794, anticorps DM2-MMP, anticorps Dm2-MMP, anticorps Dmel\\CG1794, anticorps MMP2, anticorps anon-WO0118547.84, anticorps dm-2MMP, anticorps dmmp2, anticorps l(2)02353, anticorps mmp2, anticorps wu:fa99h12, anticorps wu:fk89d01, anticorps fgmmp-2, anticorps Mmp-2, anticorps LOC100135793, anticorps Clg4a, anticorps GelA, anticorps MMP-2, anticorps CLG4, anticorps CLG4A, anticorps MMP-II, anticorps MONA, anticorps TBE-1, anticorps matrix metallopeptidase 2, anticorps Matrix metalloproteinase 2, anticorps matrix metalloproteinase 2, anticorps matrix metalloproteinase-2, anticorps MMP2, anticorps Mmp2, anticorps mmp2, anticorps LOC657982, anticorps LOC100135793
    Sujet
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    73882
    ID gène
    4313
    NCBI Accession
    NP_001121363, NP_004521
    UniProt
    P08253
    Pathways
    Activation of Innate immune Response
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