TRAF3 anticorps (C-Term)

N° du produit ABIN657866

L’anticorps anti-TRAF3 Polyclonal Lapin est utilisé pour la détection de TRAF3 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour TRAF3 anticorps (C-Term) (ABIN657866)

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3 est non-conjugé

Application: Western Blotting (WB)

Clone: RB22535

Détail du produit anti-TRAF3 anticorps

Épitope: AA 490-517, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TRAF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-517 amino acids from the C-terminal region of human TRAF3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TRAF3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur TRAF3

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Autre désignation: TRAF3

Sujet: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Poids moléculaire: 64490

ID gène: 7187

NCBI Accession: NP_001186356, NP_003291, NP_663777, NP_663778

UniProt: Q13114

Pathways: Signalisation NF-kappaB, Apoptose, Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades