TRPV1 anticorps (N-Term)

N° du produit ABIN657909

Détail du produit anti-TRPV1 anticorps

Antigène: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Épitope: AA 124-153, N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPV1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TRPV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the N-terminal region of human TRPV1.

Clone: RB33721

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TRPV1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-TRPV1 (ABIN657909)

Miyano, Minami, Yokoyama, Ohbuchi, Yamaguchi, Murakami, Shiraishi, Yamamoto, Matoba, Uezono: "Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity." dans: Anesthesia and analgesia, Vol. 120, Issue 4, pp. 790-8, (2015) (PubMed).

Détails sur TRPV1

Antigène: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Autre désignation: TRPV1 (TRPV1 Produits)

Synonymes: anticorps si:dkey-9e15.2, anticorps VR.5'sv, anticorps Vr1, anticorps Vr1l1, anticorps VR1, anticorps OTRPC1, anticorps TRPV1alpha, anticorps TRPV1beta, anticorps VR-1, anticorps transient receptor potential cation channel, subfamily V, member 1, anticorps transient receptor potential cation channel subfamily V member 1, anticorps trpv1, anticorps Trpv1, anticorps TRPV1

Sujet: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Poids moléculaire: 94956

ID gène: 7442

NCBI Accession: NP_061197, NP_542435, NP_542436, NP_542437

UniProt: Q8NER1

Pathways: Dicarboxylic Acid Transport