FGF8 anticorps (AA 141-190)

N° du produit ABIN6579254

L’anticorps anti-FGF8 Polyclonal Lapin est utilisé pour la détection de FGF8 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour FGF8 anticorps (AA 141-190) (ABIN6579254)

Antigène: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FGF8 anticorps

Épitope: AA 141-190

Fonction: FGF-8 Antibody

Specificité: FGF-8 Polyclonal Antibody detects endogenous levels of FGF-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human FGF8. AA range:141-190

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FGF8

Antigène: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Autre désignation: FGF8

Sujet:

Synonyms: FGF8, AIGF, Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8

Background: The protein encoded byThis gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene re

Gene Name: FGF8

Protein Name: Fibroblast growth factor 8

Poids moléculaire: 26 kDa

ID gène: 2253

OMIM: 600483

UniProt: P55075

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis