Neuregulin 1 anticorps (AA 21-242)

N° du produit ABIN6654437

Cet anticorps anti-Neuregulin 1 Monoclonal Souris (Clone NRG1-2752) (ABIN6654437) détecte spécifiquement Neuregulin 1 dans ELISA et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Neuregulin 1 anticorps (AA 21-242) (ABIN6654437)

Antigène: Neuregulin 1 (NRG1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuregulin 1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Classe de qualité: Carrier-free

Clone: NRG1-2752

Détail du produit anti-Neuregulin 1 anticorps

Épitope: AA 21-242

Fonction: Neuregulin-1 Antibody / NRG1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 21-242 from the human protein was used as the immunogen for this Neuregulin-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Neuregulin-1 antibody to be titered up or down for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Neuregulin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Neuregulin 1

Antigène: Neuregulin 1 (NRG1)

Autre désignation: Neuregulin-1

Sujet: Heregulin-1 / Neuregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

UniProt: Q02297

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation