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TLR8 anticorps

Cet anticorps anti-TLR8 est un anticorps Souris Monoclonal détectant TLR8 dans WB, IHC, IF, FACS et DB. Adapté pour Humain.
Rockland
N° du produit ABIN6655316
N° du produit (Fournisseur): 200-301-i30

Aperçu rapide pour TLR8 anticorps (ABIN6655316)

Antigène

Voir toutes TLR8 Anticorps
TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité

  • 80
  • 46
  • 35
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 79
  • 11
  • 2
  • 1
Souris

Clonalité

  • 81
  • 12
Monoclonal

Conjugué

  • 37
  • 9
  • 9
  • 8
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp TLR8 est non-conjugé

Application

  • 68
  • 39
  • 26
  • 13
  • 13
  • 11
  • 11
  • 10
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Dot Blot (DB)

Clone

44C143
  • N° du produit (Fournisseur)

    200-301-i30

    Fournisseur

    Rockland

    Fonction

    TLR8 Antibody

    Réactivité croisée (Details)

    A BLAST analysis was used to suggest cross-reactivity with Anti-TLR8 from human and mouse based on 100 % homology with the immunizing sequence.

    Purification

    Anti-TLR8 Antibody was purified by Protein G chromatography.

    Immunogène

    TLR8 Antibody was produced in mice prepared by repeated immunizations with amino acids corresponding to an internal sequence of human TLR8 protein.

    Isotype

    IgG1 kappa
  • Indications d'application

    Immunohistochemistry_Dilution: 5 μg/mL

    Flow_Cytometry_Dilution: 0.5-1 μg/10^6 cells

    Western_Blot_Dilution: 1-3 μg/mL

    Commentaires

    Anti-TLR8 Antibody is tested for use in WB, DB, Flow, Flow-CS, Flow-IC, ICC/IF, IHC, and IHC-P. Expect a band approximately 121kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Antigène

    TLR8 (Toll-Like Receptor 8 (TLR8))

    Autre désignation

    TLR8

    Sujet

    Synonyms: Toll-like receptor 8

    Background: Anti-TLR8 CD288 Antibody detects human TLR8. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa. Anti-TLR8 CD288 Antibody is ideal for investigators involved in cytokines and growth factor research.

    Gene Name: TLR8

    ID gène

    51311

    NCBI Accession

    NP_619542

    UniProt

    Q9NR97

    Pathways

    Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
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