SLC6A3 anticorps (Extracellular Loop)

N° du produit ABIN6657344

Détail du produit anti-SLC6A3 anticorps

Antigène: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Épitope: Extracellular Loop

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain, Non-Human Primate

Réactivité croisée (Details): Cross reactivity with Dopamine Transporter from other species has not been determined.

Purification: Anti-Dopamine Transporter antibody is directed against human Dopamine Transporter. Anti-Dopamine Transporter antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Dopamine Transporter antibody recognizes Dopamine Transporter from human and NHP sources.

Immunogène:

Immunogen: Anti-Dopamine Transporter Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the extracellular loop 2 region conjugated to KLH.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 1:1000

Application Note: Anti-Dopamine Transporter Antibody is suitable for use in ELISA, Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 88 kDa corresponding to DAT proteins in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur SLC6A3

Antigène: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Autre désignation: Dopamine Transporter (SLC6A3 Produits)

Synonymes: anticorps DAT, anticorps SLC6A3, anticorps Dat1, anticorps DAT1, anticorps PKDYS, anticorps solute carrier family 6 member 3, anticorps solute carrier family 6 (neurotransmitter transporter), member 3, anticorps Sodium-dependent dopamine transporter, anticorps solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, anticorps SLC6A3, anticorps slc6a3, anticorps dat-1, anticorps Slc6a3

Sujet:

Synonyms: Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3

Background: Dopamine Transporter Antibody detects dopamine transporter (DAT) which is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. Levels of DAT protein expression are altered by chronic drug administration. Anti-Dopamine Transporter Antibody is ideal for investigators involved in Neuroscience.

Gene Name: SLC6A3

ID gène: 6531

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis