CD14 anticorps (Internal Region)

N° du produit ABIN6657883

N° du produit (Fournisseur): 600-401-r04

L’anticorps anti-CD14 Polyclonal Lapin est utilisé pour la détection de CD14 dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour CD14 anticorps (Internal Region) (ABIN6657883)

Antigène: CD14

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD14 anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-r04

Fournisseur: Rockland

Fonction: CD14 Antibody

Réactivité croisée (Details): Anti-CD14 antibody is directed against mouse CD14 protein.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: CD14 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse CD14.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 0.5 μg/mL

Commentaires:

Anti-CD14 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~39.2 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet:

Synonyms: Myeloid cell-specific leucine-rich glycoprotein,CD_antigen=CD14,

Background: CD14, Cluster of differentiation 14, single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. By in situ hybridization and study of somatic cell hybrid DNA that the gene is located at bands 5q23-q31. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. This antibody is suitable for researchers interested in stem cell research.

Gene Name: CD14

ID gène: 12475

NCBI Accession: NP_033971

UniProt: P10810

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades