Leptin Receptor anticorps (Biotin)

N° du produit ABIN668260

Cet anticorps Lapin Polyclonal détecte spécifiquement Leptin Receptor dans IHC (p). Il présente une réactivité envers Mouton.

Aperçu rapide pour Leptin Receptor anticorps (Biotin) (ABIN668260)

Antigène: Leptin Receptor (LEPR)

Reactivité: Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Leptin Receptor est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Leptin Receptor anticorps (Biotin)

Réactivité croisée: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from sheep Leptin R

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Leptin Receptor

Antigène: Leptin Receptor (LEPR)

Autre désignation: Leptin receptor/Ob-R

Sujet:

Synonyms: obl, CD 295, CD295, CD295 antigen, Db, Fa, HuB219, LEP R, LEPR, LEPROT, Leptin receptor fatty, Leptin receptor gene related protein, Leptin receptor precursor, OB R, OB R gene related protein, OB receptor, OB-RGRP, Obr.

Background: Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. An OB-R transcript encodes a soluble form of the receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist. Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, an 816 amino acid residue extracellular domain, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain.

Poids moléculaire: 13kDa

Pathways: Signalistation JAK/STAT, AMPK Signaling, Feeding Behaviour