MR1 anticorps (AA 23-269)

N° du produit ABIN6719587

Détail du produit anti-MR1 anticorps

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Épitope: AA 23-269

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MR1 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Fonction: Rabbit IgG polyclonal antibody for MR1 detection. Tested with WB, FCM, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for MR1 detection. Tested with WB, FCM, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MR1 recombinant protein (Position: R23-D269).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Flow Cytometry|1-3 μg/1x106 cells Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MR1

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Autre désignation: MR1 (MR1 Produits)

Synonymes: anticorps YFV, anticorps hlals, anticorps MGC154362, anticorps MR1, anticorps DKFZp468C1823, anticorps HLALS, anticorps H2ls, anticorps Hlals, anticorps MHC class I antigen YF5, anticorps major histocompatibility complex, class I-related, anticorps major histocompatibility complex, class I-related L homeolog, anticorps YF5, anticorps MR1, anticorps mr1.L, anticorps mr1, anticorps Mr1

Sujet:

Synonyms: Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1

Background: Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

ID gène: 3140

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints