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TRADD anticorps (AA 111-230)

TRADD Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN673314
  • Antigène Voir toutes TRADD Anticorps
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-230
    Reactivité
    • 47
    • 17
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 46
    • 4
    Lapin
    Clonalité
    • 46
    • 4
    Polyclonal
    Conjugué
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRADD est non-conjugé
    Application
    • 39
    • 27
    • 26
    • 20
    • 14
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse of mouse TRADD
    Isotype
    IgG
    Top Product
    Discover our top product TRADD Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Chen, Zhang, Zhang, Li, Sun: "Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling." dans: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1304-9, (2016) (PubMed).

  • Antigène
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Autre désignation
    TRADD (TRADD Produits)
    Synonymes
    anticorps TRADD, anticorps Hs.89862, anticorps 9130005N23Rik, anticorps AA930854, anticorps wu:fc59e02, anticorps zgc:103556, anticorps tradd, anticorps TNFRSF1A associated via death domain, anticorps conjugal transfer protein D, anticorps TNFRSF1A-associated via death domain, anticorps TNFRSF1A-associated via death domain L homeolog, anticorps tnfrsf1a-associated via death domain, anticorps TRADD, anticorps traDd, anticorps Tradd, anticorps tradd.L, anticorps tradd
    Sujet

    Synonyms: AA930854, 9130005N23Rik, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tradd

    Background: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.

    ID gène
    71609
    UniProt
    Q3U0V2
    Pathways
    Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
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