TRADD anticorps (AA 1-312)

N° du produit ABIN7173904

Détail du produit anti-TRADD anticorps

Antigène: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Épitope: AA 1-312

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRADD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Humain, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRADD

Antigène: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Autre désignation: TRADD (TRADD Produits)

Synonymes: anticorps TRADD, anticorps Hs.89862, anticorps 9130005N23Rik, anticorps AA930854, anticorps wu:fc59e02, anticorps zgc:103556, anticorps tradd, anticorps TNFRSF1A associated via death domain, anticorps conjugal transfer protein D, anticorps TNFRSF1A-associated via death domain, anticorps TNFRSF1A-associated via death domain L homeolog, anticorps tnfrsf1a-associated via death domain, anticorps TRADD, anticorps traDd, anticorps Tradd, anticorps tradd.L, anticorps tradd

Sujet:

Background: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Aliases: 9130005N23Rik antibody, AA930854 antibody, TNFR1 associated DEATH domain protein antibody, TNFR1-associated DEATH domain protein antibody, TNFRSF1A associated via death domain antibody, TNFRSF1A-associated via death domain antibody, tradd antibody, TRADD_HUMAN antibody, Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody, Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody

UniProt: Q15628

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C