Presenilin 1 anticorps (Val293)
Aperçu rapide pour Presenilin 1 anticorps (Val293) (ABIN6735742)
Antigène
Voir toutes Presenilin 1 (PSEN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Val293
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Specificité
- Detects endogenous levels of the carboxy-terminal fragment of presenilin 1 (~22kD). The antibody detects the full length protein (55kD) to a lesser extent. Species cross-reactivity: Human, rat and monkey. Species sequence homology: mouse 100 % .
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Purification
- Immunoaffinity purified
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Immunogène
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Synthetic peptide (KLH coupled) corresponding to residues around valine 293 of human presenilin 1.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Indications d'application
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Approved: ELISA, IP (1:100), WB (1:500)
Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:500. Immunoprecipitation: 1:100. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Presenilin 1 (PSEN1)
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Autre désignation
- PSEN1 / Presenilin 1
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Sujet
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Name/Gene ID: PSEN1
Subfamily: Aspartic A22A
Family: protease
Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1 -
ID gène
- 5663
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UniProt
- P49768
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Pathways
- Signalisation Notch, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Antigène
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