CCL2 anticorps

N° du produit ABIN675863

L’anticorps Lapin Polyclonal anti-CCL2 a été validé pour WB, IHC (p) et IF (p). Il convient pour détecter CCL2 dans des échantillons de Humain, Souris, Rat, Chien, Porc et Boeuf (Vache). Il y a 3+ publications disponibles.

Aperçu rapide pour CCL2 anticorps (ABIN675863)

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CCL2 anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CCL2

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Références pour anticorps anti-CCL2 (ABIN675863)

Heilmann, Schinke, Bindl, Wehner, Rapp, Haffner-Luntzer, Nemitz, Liedert, Amling, Ignatius: "The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing." dans: PLoS ONE, Vol. 8, Issue 12, pp. e84232, (2014) (PubMed).

Su, Min, Cao, Yan, Zhao, Li, Chai, Mei, Yang, Zhang, Zhang, Liu, Sun, Che, Yang: "LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria." dans: Nature communications, Vol. 5, pp. 4434, (2014) (PubMed).

Kong, Luo, Li, Zhou, He: "The anti-inflammatory effect of kaempferol on early atherosclerosis in high cholesterol fed rabbits." dans: Lipids in health and disease, Vol. 12, pp. 115, (2013) (PubMed).

Détails sur CCL2

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Autre désignation: MCP1/CCL2

Sujet:

Synonyms: C-C motif chemokine 2, HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2, CCL-2, MCP1, SCYA2

Background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Poids moléculaire: 11kDa

ID gène: 6347

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2