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TP53BP1 anticorps (pSer25, pSer29)

TP53BP1 Reactivité: Humain, Souris, Rat ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN682993
  • Antigène Voir toutes TP53BP1 Anticorps
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Épitope
    • 20
    • 15
    • 14
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer25, pSer29
    Reactivité
    • 94
    • 49
    • 46
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 96
    • 10
    • 2
    • 1
    Lapin
    Clonalité
    • 88
    • 21
    Polyclonal
    Conjugué
    • 60
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TP53BP1 est non-conjugé
    Application
    • 46
    • 27
    • 27
    • 26
    • 26
    • 20
    • 18
    • 13
    • 11
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29
    Isotype
    IgG
    Top Product
    Discover our top product TP53BP1 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: "Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." dans: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).

  • Antigène
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Autre désignation
    p53BP1 + (TP53BP1 Produits)
    Synonymes
    anticorps TP53BP1, anticorps MGC160112, anticorps 53BP1, anticorps Tp53bp1, anticorps m53BP1, anticorps p202, anticorps Trp53bp1, anticorps tumor protein p53 binding protein 1, anticorps tumor suppressor p53-binding protein 1, anticorps tumor protein p53 binding protein 1 (predicted), 5 prime, anticorps transformation related protein 53 binding protein 1, anticorps TP53BP1, anticorps tp53bp1, anticorps LOC100550605, anticorps Trp53bp1, anticorps Tp53bp1
    Sujet

    Synonyms: p202, 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1, TP53BP1

    Background: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

    ID gène
    7158
    UniProt
    Q12888
    Pathways
    Réparation de l'ADN
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