TP53BP1 anticorps (N-Term)

N° du produit ABIN2855433

Détail du produit anti-TP53BP1 anticorps

Antigène: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53BP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to 53BP1 (tumor protein p53 binding protein 1)
53BP1 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human 53BP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , HeLa , Neuro 2A , C8D30 , NIH-3T3

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TP53BP1

Antigène: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Autre désignation: tumor protein p53 binding protein 1 (TP53BP1 Produits)

Synonymes: anticorps TP53BP1, anticorps MGC160112, anticorps 53BP1, anticorps Tp53bp1, anticorps m53BP1, anticorps p202, anticorps Trp53bp1, anticorps tumor protein p53 binding protein 1, anticorps tumor suppressor p53-binding protein 1, anticorps tumor protein p53 binding protein 1 (predicted), 5 prime, anticorps transformation related protein 53 binding protein 1, anticorps TP53BP1, anticorps tp53bp1, anticorps LOC100550605, anticorps Trp53bp1, anticorps Tp53bp1

Sujet: May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

Cellular Localization: Nucleus , Kinetochore

Poids moléculaire: 214 kDa

ID gène: 7158

UniProt: Q12888

Pathways: Réparation de l'ADN