SNAI1, SNAI2, SNAI3 (AA 188-264) anticorps

N° du produit ABIN685597

Détail du produit

Antigène: SNAI1, SNAI2, SNAI3

Épitope: AA 188-264

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Réactivité croisée: Humain, Lapin

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Snail

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Takahashi, Akamatsu, Yagami, Hasegawa, Ohgo, Abe, Iwata, Arima, Mizutani, Nakata, Matsunaga: "Epithelial-mesenchymal transition of the eccrine glands is involved in skin fibrosis in morphea." dans: The Journal of dermatology, Vol. 40, Issue 9, pp. 720-5, (2013) (PubMed).

Détail du antigène

Antigène: SNAI1, SNAI2, SNAI3

Synonymes: anticorps SLUGH2, anticorps SNA, anticorps SNAH, anticorps SNAIL, anticorps SNAIL1, anticorps dJ710H13.1, anticorps snail family transcriptional repressor 1, anticorps SNAI1

Sujet:

Synonyms: dJ710H13.1, Protein sna, Protein snail homolog, SLUGH2, SNA, Sna protein, SNAH, SNAI1, Snail homolog 1 Drosophila, Zinc finger protein SNAI1, SNAI1_HUMAN, Protein snail homolog 1, dJ710H13.1, SNAIL, SNAIL1, Protein sna, SLUG, WS2D, SLUGH, SLUGH1, SNAIL2, SMUC, SNAIL3, ZNF293, Zfp293

Background: The zinc finger transcription factor 'SNAIL' was first identified in Drosophila and, along with 'twist', a basic helix-loop-helix transcription factor, is indispensable for mesoderm formation. SNAIL is a repressor of mouse E-cadherin transcription, with expression of SNAIL inversely correlated with expression of E-cadherin. Abnormal expression of SNAIL could underlie the tumorigenic conversion of epithelia associated with loss of E-cadherin expression through screening mouse and human cell lines and by in situ hybridization of primary human tumors undergoing malignant progression.

Poids moléculaire: 29kDa

ID gène: 6615, 6591, 333929

UniProt: Q02085, P97469, Q9QY31