BMP4 anticorps (AA 251-350)

N° du produit ABIN685642

Cet anticorps Lapin Polyclonal détecte spécifiquement BMP4 dans WB, ELISA et IHC (p). Il présente une réactivité envers Souris et Mouton et a été mentionné dans 1 publication.

Aperçu rapide pour BMP4 anticorps (AA 251-350) (ABIN685642)

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivité: Souris, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BMP4 anticorps

Épitope: AA 251-350

Réactivité croisée: Souris, Mouton

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat BMP4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-BMP4 (ABIN685642)

Wang, Zhao, Wang: "Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway." dans: Brain research, Vol. 1560, pp. 18-26, (2014) (PubMed).

Détails sur BMP4

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Autre désignation: BMP4

Sujet:

Synonyms: BMP 4, BMP2B, BMP2B1, Bone morphogenetic protein 4, DVR4, ZYME, BMP4_HUMAN, BMP-4, Bone morphogenetic protein 2B, BMP-2B.

Background: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development