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BIRC6 anticorps (AA 4701-4857)

BIRC6 Reactivité: Humain ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN687292
  • Antigène Voir toutes BIRC6 Anticorps
    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
    Épitope
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4701-4857
    Reactivité
    • 25
    • 4
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 21
    • 2
    • 2
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BIRC6 est non-conjugé
    Application
    • 12
    • 11
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Apollon
    Isotype
    IgG
    Top Product
    Discover our top product BIRC6 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
    Autre désignation
    Apollon/BIRC6 (BIRC6 Produits)
    Synonymes
    anticorps APOLLON, anticorps BRUCE, anticorps bruce, anticorps apollon, anticorps BIRC6, anticorps A430032G04Rik, anticorps A430040A19Rik, anticorps AA501170, anticorps Bruce, anticorps D630005A10Rik, anticorps mKIAA1289, anticorps baculoviral IAP repeat containing 6, anticorps baculoviral IAP repeat-containing 6, anticorps BIRC6, anticorps Birc6, anticorps birc6
    Sujet

    Synonyms: BRUCE, APOLLON, Baculoviral IAP repeat-containing protein 6, BIR repeat-containing ubiquitin-conjugating enzyme, Ubiquitin-conjugating BIR domain enzyme apollon, BIRC6, KIAA1289

    Background: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

    ID gène
    57448
    UniProt
    Q9NR09
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