XRCC6/XRCC5 anticorps (PE)

N° du produit ABIN6933804

Détail du produit anti-XRCC6/XRCC5 anticorps (PE)

Antigène: XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRCC6/XRCC5 est conjugé à/à la PE

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Test (T)

Specificité: Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Aucune reactivité croisée: Poulet, Souris, Rat (Rattus)

Purification: Purified by Protein A/G

Immunogène: Nuclear extract of human HL-60 cells

Clone: KU729

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Human cancer K562, HL-60, HEp-2 or HeLa cells.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100 for 30 minutes at RT),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur XRCC6/XRCC5

Antigène: XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))

Autre désignation: XRCC6 (p70) & XRCC5 (p80) (XRCC6/XRCC5 Produits)

Poids moléculaire: 70kDa & 80kDa

ID gène: 2547, 7520

UniProt: P12956, P13010