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CD14 anticorps

CD14 Reactivité: Humain FACS, IF Hôte: Souris Monoclonal LPSR-927 unconjugated

N° du produit ABIN6936599

Fiche de données

Antigène Voir toutes CD14 Anticorps

CD14
Reactivité
228

38

32

25

24

18

17

15

14

14

13

10

9

9

8

8

8

5

2

2

2

1

1

1
Humain
Hôte
202

44

25

3

1
Souris
Anticorps secondaires appropriés
Clonalité
230

45
Monoclonal
Conjugué
116

29

21

15

14

8

5

5

5

4

4

4

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD14 est non-conjugé
Application
205

83

57

54

49

44

21

13

12

12

7

6

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Specificité

Recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

Réactivité croisée (Details)

Human.

Purification

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène

Recombinant human CD14 protein

Clone

LPSR-927

Isotype

IgG1 kappa

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CD14 Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 1A3B6 unconjugated

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CD14 Reactivité: Humain FACS, WB, IHC, ELISA, IF Hôte: Souris Monoclonal 14G1F3 unconjugated

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CD14 Reactivité: Humain FACS, WB, IHC, ELISA Hôte: Souris Monoclonal 1D1F8 unconjugated

anti-CD14 (CD14) (AA 25-148) antibody
CD14 Reactivité: Humain FACS, WB, IHC, ISt, StM Hôte: Souris Monoclonal LPSR-2385 unconjugated

anti-CD14 (CD14) antibody
CD14 Reactivité: Humain, Non-Human Primate FACS, WB, ELISA, IP Hôte: Souris Monoclonal MEM-18 unconjugated

anti-CD14 (CD14) antibody
CD14 Reactivité: Humain, Non-Human Primate FACS, WB, ELISA, IP, Func Hôte: Souris Monoclonal MEM-18 unconjugated

anti-CD14 (CD14) antibody (Biotin)
CD14 Reactivité: Humain, Non-Human Primate FACS, WB, ELISA, IP Hôte: Souris Monoclonal MEM-18 Biotin

Indications d'application

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 cells and human monocytes. Lymph nodes and tonsils.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur

Azide free

Stock

-20 °C,-80 °C

Stockage commentaire

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption

24 months
Antigène

CD14

Autre désignation

CD14 (CD14 Produits)

Synonymes

anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14

Sujet

Lipopolysaccharide receptor, LPS-R, LPSR, Mo2, Monocyte Differentiation Antigen 14, Myeloid cell-specific leucine-rich glycoprotein,CD14 (Monocyte / Macrophage Marker)
Cellular localisation: Cell Surface

Poids moléculaire

55kDa

ID gène

929, 163867

UniProt

P08571

Pathways

Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades