CD28 anticorps

N° du produit ABIN6936659

Cet anticorps Souris Monoclonal détecte spécifiquement CD28 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD28 anticorps (ABIN6936659)

Antigène: CD28

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est non-conjugé

Application: ELISA

Clone: C28-77

Détail du produit anti-CD28 anticorps

Fonction: CD28 Antibody

Specificité: Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human CD28 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells. Human lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet:

T-cell-specific surface glycoprotein CD28, Tp44

Jurkat cells. Human lymph nodes and tonsils.

Poids moléculaire: 44kDa (monomer), 88kDa (dimer)

ID gène: 940, 591629

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response