Gastrin anticorps

N° du produit ABIN6937299

Détail du produit anti-Gastrin anticorps

Antigène: Gastrin (GAST)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Gastrin est non-conjugé

Application: ELISA, Coating (Coat)

Specificité: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human GAST protein

Clone: GAST-2635

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.

Positive_Control: Human Pituitary or Stomach.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: GAST (GAST Produits)

Synonymes: anticorps GAS, anticorps Gas, anticorps PPG34, anticorps GAST, anticorps gastrin, anticorps GAST, anticorps Gast

Sujet: Component II, GAS, Gast, Gastrin component I, Gastrin component II, Gastrin component III, Gastrin precursor, Gastrin-14, Gastrin-17, Gastrin-34, Gastrin-52, Gastrin-6, Gastrin-71,Gastrin
Cellular localisation: Secreted.

Poids moléculaire: 2/4/14kDa

ID gène: 2520, 2681

UniProt: P01350