Recombinant GP2 anticorps (AA 35-179)

N° du produit ABIN6937336

Détail du produit anti-GP2 anticorps

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Type d'anticorp: Recombinant Antibody

Épitope: AA 35-179

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GP2 est non-conjugé

Application: ELISA, Western Blotting (WB), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Human. Does not react with Mouse.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human GP2 protein fragment (around aa35-179) (exact sequence is proprietary)

Clone: GP2-2569R

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: PANC-1 cells. Pancreas.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur GP2

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Autre désignation: GP2 (GP2 Produits)

Synonymes: anticorps ZAP75, anticorps 2310037I18Rik, anticorps AV060639, anticorps gp80, anticorps glycoprotein 2, anticorps glycoprotein 2 (zymogen granule membrane), anticorps GP2, anticorps Gp2

Classe de substances: Viral Protein

Sujet: Glycoprotein 2 (zymogen granule membrane), GP2, Pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75,GP2 (Glycoprotein 2) / ZAP75
Cellular localisation: Cell Surface and Secreted

Poids moléculaire: 59kDa

ID gène: 2813, 53985

UniProt: P55259