Neuregulin 1 anticorps (AA 21-242)

N° du produit ABIN6938089

Cet anticorps anti-Neuregulin 1 est un anticorps Souris Monoclonal détectant Neuregulin 1 dans ELISA, IF et Coat. Adapté pour Humain.

Aperçu rapide pour Neuregulin 1 anticorps (AA 21-242) (ABIN6938089)

Antigène: Neuregulin 1 (NRG1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuregulin 1 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Coating (Coat)

Clone: NRG1-2752

Détail du produit anti-Neuregulin 1 anticorps

Épitope: AA 21-242

Specificité: Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment of human Neuregulin-1 (NRG1) protein (around aa 21-242) (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: A431, MCF-7 or T47D cells. Breast, Bladder or Thyroid Carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Neuregulin 1

Antigène: Neuregulin 1 (NRG1)

Autre désignation: NRG1

Sujet: Acetylcholine receptor-inducing activity (ARIA), Breast cancer cell differentiation factor p45, Glial growth factor (GGF2), Heregulin-1, Heregulin, alpha (45kD, ERBB2 p185-activator), HGL, HRG1, HRGA, MST131, Neu Differentiation Factor (NDF), Neuregulin-1, NRG1, Sensory and Motor Neuron-Derived Factor (SMDF),Heregulin-1 / Neuregulin-1 (Breast and Urothelial Marker)
Cellular localisation: Cell Surface and Cytoplasmic (Secreted)

Poids moléculaire: 26-71kDa

ID gène: 3084, 453951, 668810

UniProt: Q02297

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation