SERPINA3 anticorps (AA 49-187)

N° du produit ABIN6939169

Détail du produit anti-SERPINA3 anticorps

Antigène: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Épitope: AA 49-187

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SERPINA3 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificité: It recognizes a protein of 65-76 kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.

Purification: Purified by Protein A/G

Immunogène: Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49-187) (exact sequence is proprietary)

Clone: AACT-1451

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HeLa cells. Tonsil, Pancreas or Histiocytoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur SERPINA3

Antigène: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Autre désignation: SERPINA3 (SERPINA3 Produits)

Synonymes: anticorps SERPINA3-1, anticorps Pi2, anticorps AACT, anticorps ACT, anticorps GIG25, anticorps A1AT, anticorps PI, anticorps alpha-1-PI, anticorps AAT, anticorps Pi, anticorps Spi1, anticorps SERPINA3-5, anticorps serpina3, anticorps serpin A3-5, anticorps serpin family A member 3, anticorps alpha-1-antiproteinase F precursor, anticorps serpin family A member 1, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog, anticorps LOC396684, anticorps SERPINA3, anticorps LOC100008973, anticorps SERPINA1, anticorps Serpina1, anticorps SPIA5, anticorps serpina3.L

Poids moléculaire: 65-76kDa

ID gène: 12

UniProt: P01011