TRIM29 anticorps (AA 1-200)

N° du produit ABIN6939434

Détail du produit anti-TRIM29 anticorps

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Épitope: AA 1-200

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRIM29 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)

Specificité: It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein

Clone: TRIM29-1041

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: Human tonsil or squamous cell carcinoma.

Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TRIM29

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Autre désignation: TRIM29 (TRIM29 Produits)

Synonymes: anticorps ATDC, anticorps 1110047J21Rik, anticorps 2810431N19Rik, anticorps 4732461M22Rik, anticorps AI119726, anticorps MGC53484, anticorps TRIM29, anticorps atdc, anticorps tripartite motif containing 29, anticorps tripartite motif-containing 29, anticorps tripartite motif containing 29 L homeolog, anticorps TRIM29, anticorps Trim29, anticorps trim29.L, anticorps trim29

Poids moléculaire: 66kDa

ID gène: 23650

UniProt: Q14134

Pathways: Signalisation p53, Apoptose, Réparation de l'ADN, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus