NADPH Oxidase 4 anticorps

N° du produit ABIN6940247

L’anticorps Souris Monoclonal anti-NADPH Oxidase 4 a été validé pour WB, ELISA et Coat. Il convient pour détecter NADPH Oxidase 4 dans des échantillons de Humain.

Aperçu rapide pour NADPH Oxidase 4 anticorps (ABIN6940247)

Antigène: NADPH Oxidase 4 (NOX4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NADPH Oxidase 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: NOX4-1245

Détail du produit anti-NADPH Oxidase 4 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant human NOX4 protein

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: PC-12, JAR cells. Kidney.

Known Application: ELISA (For coating, order Ab without BSA)Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NADPH Oxidase 4

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NOX4

Sujet: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

Poids moléculaire: 70kDa

ID gène: 50507

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration